Data and code for: More Is Not Always Better: A Parsimonious Analysis of Metabolic Immune Checkpoint Genes Identifies the CD73/CD39 Axis as the Dominant Prognostic Component in Lung Adenocarcinoma.

Reproducibility package for the manuscript analyzing a four-gene metabolic immune-checkpoint panel (VSIR, CD38, ENTPD1, NT5E) in lung adenocarcinoma. Contains the processed TCGA-LUAD analysis dataset (n = 497, 180 deaths), R scripts that reproduce all figures, tables, and statistics, and the generated results and figures. Raw public data (TCGA-LUAD expression and GDC phenotype from UCSC Xena/GDC; GSE68465 from NCBI GEO) are not redistributed; GSE68465 is downloaded automatically by the validation script. See README.txt for full instructions. Funded by the Deanship of Scientific Research, Northern Borders University, grant NBU-FFR-2026-2088-03.