Uterine rupture: up to date

The uterine rupture is a dramatic obstetrical event, fortunately unusual. Unfortunately, onset is often sudden, very often during pregnancy, in the third trimester, and during labor. The uterine rupture depends on a number of biological and mechanical factors, in which the muscular scarring process is the main responsible factor. The biology of uterine muscle scarring depends on a set of biomolecular processes involving growth factors, neurotransmitters, neoangiogenesis, deposition and reabsorption of collagen fibers, ect. Any interference in this precess creates the conditions for the uterine rupture, which occurs under contract, during the maximum muscular tension. Separation of the fibers almost always involves a traumatic vascular interruption with copious haemorrhage. Here is why uterine rupture is a very rare event, but very dangerous for the life of the woman and the fetus inside it.