Bruton's tyrosine kinase (BTK) with GDC-0853
收藏Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5vfi
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Bruton's tyrosine kinase (BTK) with GDC-0853 Descriptor: 1,2-ETHANEDIOL, 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, SULFATE ION, ... Authors: Steinbacher, S, Eigenbrot, C. Deposit date: 2017-04-07 Release date: 2018-02-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development. J. Med. Chem., 61, 2018
创建时间：
2017-04-07
