PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES
收藏ESRF Portal2028-01-01 更新2026-04-23 收录
下载链接：
https://doi.esrf.fr/10.15151/ESRF-ES-2231628049
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资源简介：
The outstanding research questions of our BAG (now expanded to 9 PIs) focus on proteins and their complexes involved in a variety of processes, ranging from cell homeostasis (from gene regulation to folding quality control, from energy metabolism to signal transduction) to communication and surface recognition (including trans-interactions between cell adhesion molecules, components of the extracellular matrix weaving, as well as antigen-antibody interactions for vaccine development and optimization). Key to several projects is the characterization of the mechanisms associated to enzyme function in various organisms, including bacteria, viruses, plants, animals and humans for downstream drug discovery campaigns. Emphasis is also given to research focusing on engineering protein and enzymes for future industrial applications, as well as to understand the impact of pathogenic mutations on protein structures, providing a genotype-to-molecular phenotype rationale to disease development.
提供机构：
University of Ljubljana, Department of Biochemistry, Faculty of Chemistry and Chemical Technology, Vecna Pot 113, 1000 Ljubljana, Slovenia; University of Pavia, Dept. Biology and Biotechnology, via Ferrata 1, 27100 Pavia, Italy; University of Pavia, Laboratory Immunology and General Pathology, Department of Molecular Medicine, Via Ferrata, 9, 27100 Pavia, Italy; University of Pavia, Laboratory Immunology and General Pathology, Department of Molecular Medicine Via Ferrata, 9, 27100, Pavia, ITALY
创建时间：
2028-01-01
