官方服务：
资源简介：
CDK inhibitor PHA-793887 profiling on A2780
应用场景：
创建时间：
2010-07-14
相关数据集
N ‑2-(Phenylamino) Benzamide Derivatives as Dual Inhibitors of COX‑2 and Topo I Deter Gastrointestinal Cancers via Targeting Inflammation and Tumor Progression
Given the close association between inflammation and cancer, combining anti-inflammation therapy is prominent to improve the anticancer effect. Based on I-1, a series of agents targeting COX-2 and Top
NIAID Data Ecosystem60
Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) has the potential to directly limit NAD production in cancer cells and is an effective strategy for cancer treatment. Using a structure-bas
NIAID Data Ecosystem50
Real-world Application of the Oral Factor B Inhibitor Iptacopan in Chinese Patients with Paroxysmal Nocturnal Hemoglobinuria: A Four-case Series Data
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, and potentially life-threatening clonal hematopoietic stem cell disorder. PNH predominantly affects individuals aged 30–40 years with a g
NIAID Data Ecosystem10
E-MTAB-6620
RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
NIAID Data Ecosystem60
Noncovalent Protein Arginine Deiminase (PAD) Inhibitors Are Efficacious in Animal Models of Multiple Sclerosis
Peptidyl arginine deiminases have been shown to be hyperactive in neurodegenerative diseases including multiple sclerosis. An α-amino acid-based core structure, derived from a hydantoin core, with uni
NIAID Data Ecosystem30
