DP4 epitopes binding ability and proliferative response in HLA-A2/DP4 mice.
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https://figshare.com/articles/dataset/_DP4_epitopes_binding_ability_and_proliferative_response_in_HLA_A2_DP4_mice_/342878
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Twelve HLA-DP4-restricted epitopes were predicted by scanning the entire HBs protein and were synthesized. Exp IC50 (nM) represents the predicted affinities according to algorithms, while Obs (nM) represents the affinities obtained from MHC class II binding assays. [3H]thymidine incorporation assays were used to measure the proliferation of CD4+ T cells from DNA-vaccine-immunized HLA-A2/DP4 and H-2 class II-deficient mice stimulated with the twelve synthesized peptides, including the previously reported epitope, S181–192. Exp = Expected, Obs = Observed, SI, stimulation index.
创建时间：
2015-12-02
