The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression

ChEBI2011-01-21 更新2026-07-21 收录

癌症分子机制

p53信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-26763 数据链接链接失效反馈

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The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression

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2011-01-21

Additional file 3 of ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner

癌症分子机制

依赖性基因调控

Additional file 3. Overexpression of ALKBH5 decreased the proliferation capacity in 2 HCC cell lines, while co-overexpressed of PAQR4 reverted this phenomenon (A and B). Overexpression of ALKBH5 decre

NIAID Data Ecosystem30

β-arrestin1 is involved in hepatocellular carcinogenesis via an inflammation-mediated Akt signal

癌症分子机制

基因表达谱分析

Hepatocellular carcinoma (HCC), the main form of liver cancer, is the sixth most common cancer and the third most frequent cause of cancer death worldwide1. The exact mechanism of HCC initiation and d

NIAID Data Ecosystem30

A renal cancer-associated, renal tubule-specific, HIF-binding enhancer of oncogenic MYC and PVT1 expression. Homo sapiens

癌症分子机制

MYC转录因子

Clear cell renal cell carcinoma is characterized by loss of function of the von Hippel-Lindau tumor suppressor gene (VHL) and unrestrained activation of hypoxia inducible transcription factors (HIF).

NIAID Data Ecosystem30

WTX overexpression effect on gastric cell line

癌症分子机制

肿瘤抑制基因

We used microarrays to detail the global gene expression in AGS gastric cancer cells overexpressing WTX, a tumor suppressor frequently inactivated in Wilms tumor. Results provide insight into roles fo

NIAID Data Ecosystem30

DataSheet4_PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.zip

癌症分子机制

细胞周期调控

The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,

NIAID Data Ecosystem30

The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression

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