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Identification of Pol II(G) target genes in mouse liver [ChIP-seq]
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP244621
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资源简介：
To investigate the biological role of Pol II(G), we identified Pol II(G) target genes in normal mouse liver. Overall design: To identify genes that are directly targeted by Pol II(G) in hepatocytes, we performed ChIP-seq analysis with non-crosslinked chromatin prepared from Gdown1 flox/flox (FF) or Gdown1flox/flox;Alb-Cre (KO) liver at 7W of age. We also analyzed Gdown1 target genes in p53KO hepatocytes. For the negative control, tamoxifen (TAM)-inducible Gdown1flox/floxKO mice carrying both the Alb-CreERT2 transgene and a p53 null mutation was used.
创建时间：
2021-01-11
