Supporting data for “Protective Effects of Some Flavonoid Derivatives against Acrolein and Glycidol-induced Toxicities in Endothelial Cells

This dataset serves as supporting information
for the thesis “Protective Effects of Some Flavonoid Derivatives against
Acrolein and Glycidol-induced Toxicities in Endothelial Cells”, Acrolein and glycidyl
esters are lipid-derived toxicants that widely occur in processed foods. Toxicological
evaluation of acrolein and glycidol was conducted in vivo using human umbilical
vein endothelial cells (HUVECs). In addition, a series of flavonoid
derivatives, stilbenoid-fused naringenin, were synthesized and screened for
their protective efficacy. The data includes statistical analysis from flow
cytometry, immunoblot assay, ELISA, qRT-PCR results in HUVECs.

本数据集作为论文《某些黄酮衍生物对丙烯醛和缩水甘油酯诱导的血管内皮细胞毒性的保护作用》的辅助信息。丙烯醛与缩水甘油酯为脂质衍生的有毒物质，广泛存在于加工食品中。本研究通过使用人脐静脉内皮细胞（HUVECs）进行了丙烯醛与缩水甘油的体内毒理学评价。此外，合成了一系列黄酮衍生物，包括 Stilbenoid-fused naringenin，并对其保护效力进行了筛选。数据包括在 HUVECs 中通过流式细胞术、免疫印迹、ELISA 和定量实时PCR（qRT-PCR）得到的统计分析结果。