VCB in complex with VHL-binding compound 82
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VCB in complex with VHL-binding compound 82 Descriptor: (2~{S},4~{R})-1-[(2~{S})-1-(1-fluoranylcyclopropyl)carbonylpiperidin-2-yl]carbonyl-~{N}-[(1~{S})-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... Authors: Braun, M.B, Dierlamm, N, Hartmann, M.D. Deposit date: 2025-03-07 Release date: 2025-04-23 Last modified: 2025-11-19 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability. J.Med.Chem., 68, 2025
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2025-03-07
