CryoEM structure of human gamma-secretase in complex with E2012 and L685458
收藏Protein Data Bank Japan2025-07-02 更新2026-03-21 收录
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CryoEM structure of human gamma-secretase in complex with E2012 and L685458 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yang, G, Zhou, R, Guo, X, Lei, J, Yan, C, Shi, Y. Deposit date: 2020-10-11 Release date: 2021-01-27 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of gamma-secretase inhibition and modulation by small molecule drugs. Cell, 184, 2021
创建时间：
2020-10-11
