File S1 - Designed Chemical Intervention with Thiols for Prophylactic Contraception

The supporting Information contains physicochemical characterization data and synthesis details of PPC (Figure S1) and its derivatives (Figure S3); proposed reaction of PPC (Figure S2) and its derivatives (Figure S4) with sperm proteins; the spermicidal activity of reactants and the product PPC (Table S1); NMR spectra of PPC derivatives viz. BPC (Figure S5), IPC (Figure S6) and HPC (Figure S7); optimization details of film formulation for PPC (Table S2) and a typical HPLC chromatogram of PPC (Figure S8). (PDF)