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Huntington disease mice exhibit a TCF7L2-responsive suppression of both homeostatic and compensatory remyelination

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181370
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PDGFRA-EGFP+ striaal cells were isolated for bulk RNA-sequencing from R6/2 (6wk and 12wk) and zQ175 (12wk and 1yr) HD mice and littermate controls. RNA was extracted from FACS isolated PDGFRA-EGFP+ striatal cells of R6/2 (6wk and 12wk) and zQ175 (12wk and 1yr) HD mice and littermate controls using Qiagen Rneasy Plus Mini kits. Libraries were generated using the TruSeq RNA v2 kit and sequenced on an Illumina HiSeq 2500 (Paired-end 125 bp).
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2022-10-31
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