Structure of binary complex of human cGAS and bound ppp(2'-5')GpG
收藏Protein Data Bank Japan2024-05-29 更新2026-04-19 收录
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Structure of binary complex of human cGAS and bound ppp(2'-5')GpG Descriptor: Cyclic GMP-AMP synthase, ZINC ION, [[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate Authors: Wu, S, Sohn, J. Deposit date: 2023-04-17 Release date: 2024-04-24 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
创建时间:
2023-04-17



