RNA Sequencing of mouse E15.5 Six2-Cre; Irx3/5(loxP/loxP) whole kidneys

Transcriptional profiling of E15.5 whole kidneys with a conditional deletion of Irx3/5 in the nephron progenitor cell lineage. Irx3/5 were conditionally deleted using Six2-driven Cre-recombinase. Data will provide novel insight into the functional contributions of Irx3/5 towards nephrogenesis. Whole kidney pairs were collected from E15.5 Six2-Cre; Irx3/5(loxP/loxP) and Irx3/5(loxP/+) littermate control embryos. RNA was extracted from the collected kidney samples and processed for RNA-sequencing.