Crystal structure of wild type HIV-1 protease in complex with GRL-10413
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of wild type HIV-1 protease in complex with GRL-10413 Descriptor: [(3~{a}~{S},4~{R},6~{a}~{R})-2,3,3~{a},4,5,6~{a}-hexahydrofuro[2,3-b]furan-4-yl] ~{N}-[(2~{S},3~{R})-1-(3-chloranyl-4-methoxy-phenyl)-4-[(4-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]-3-oxidanyl-butan-2-yl]carbamate, protease Authors: Yedidi, R.S, Delino, N.S, Das, D, Kaufman, J.D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. Deposit date: 2016-06-01 Release date: 2016-08-31 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413. Antimicrob.Agents Chemother., 60, 2016
创建时间：
2016-06-01
