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Transcriptomic Analysis Reveals the Molecular Mechanisms of Methylene Blue-Mediated Photodynamic Therapy Against Microsporum canis

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP636759
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Background: Microsporum canis, a primary cause of dermatophytosis, presents a growing therapeutic challenge... This study employed RNA-sequencing (RNA-Seq) to investigate the global transcriptomic response of M. canis to a sub-inhibitory concentration of MB-PDT... Conclusion: MB-PDT exerts its potent antifungal effect against M. canis through a multi-targeted mechanism that overwhelms cellular repair systems and induces PCD
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2026-01-01
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