Structure of hDM2 with Dimer Inducing Indolyl Hydantoin RO-2443
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Structure of hDM2 with Dimer Inducing Indolyl Hydantoin RO-2443 Descriptor: (5Z)-5-[(6-chloro-7-methyl-1H-indol-3-yl)methylidene]-3-(3,4-difluorobenzyl)imidazolidine-2,4-dione, E3 ubiquitin-protein ligase Mdm2 Authors: Lukacs, C.M, Janson, C.A, Graves, B.J. Deposit date: 2012-01-02 Release date: 2012-06-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization. Proc.Natl.Acad.Sci.USA, 109, 2012
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2012-01-02
