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Hepatitis C virus polymerase NS5B with thiazine inhibitor 2

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3h59
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资源简介:
Hepatitis C virus polymerase NS5B with thiazine inhibitor 2 Descriptor: N-{3-[(5S)-5-(1,1-dimethylpropyl)-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase Authors: Harris, S.F, Ghate, M. Deposit date: 2009-04-21 Release date: 2009-09-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids Bioorg.Med.Chem.Lett., 19, 2009
创建时间:
2009-04-21
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