Characterization and isolation of anti-HIV and latency reversal agents for the development of a herbal mixture

This is data for a descriptive research that describes the methods carried out on the  latency reversal activity of G. sericocephala is found in supplementary data 1. The ultra-performance liquid chromatography tandem mass spectrometry spectral data  of the solvent blank is shown in supplementary 2. Supplementary data 3 contains the ex vivo anti-HIV activity in PBMC’s. Supplementary data 4 is a summary of mean of Summary of mean potency values (IC50 ± S.D.), inhibition values at each test concentration, for the test samples, the positive control, verapamil, potency. All data in tables are expressed as mean inhibition or mean µM potency, from N ≥ 3 separate cells. The positive control value was within the acceptable potency range (0.2 - 0.8 µM). The tandem mass spectral data of lasioerin shown in supplementary 5. The nuclear magnetic resonance spectra of lasioerin are shown in supplementary data (6-11). The compound lasiocephalin  nuclear magnetic spectral data is shown in supplementary data (12-15). Supplementary data 16 shows the tandem mass spectral data of yuanhuacine A. While the nuclear magnetic resonance spectroscopy is shown in supplementary data (17-23). The compound yuanhuacine mass spectral data is shown in supplementary data 24. While the nuclear magnetic resonance spectroscopic data of yuanhuacine is shown in supplementary data (25-30). The mass spectral data of cis 2′′/3′′ isomer of gnididin is shown in supplementary data (31). While the supplementary data of cis 2′′/3′′ isomer of gnididin is shown in supplementary data (32-37). The compound yuanhuajine has its mass spectral data shown in supplementary data 38. While the nuclear magnetic spectral data of cis 2′′/3′′ isomer of gnididin is shown in supplementary data (39-42). The mass spectral data of the compound gniditrin and its proton nuclear magnetic spectral data are shown in supplementary data 43 and 44, respectively.

本数据集旨在描述一项描述性研究的实施方法，该研究探讨了丝光拟青霉菌（G. sericocephala）的延迟逆转活性，相关数据位于补充数据1中。溶剂空白样品的超高效液相色谱串联质谱光谱数据展示于补充数据2。补充数据3包含了在PBMC细胞中的体外抗HIV活性。补充数据4为测试样品、阳性对照、维拉帕米以及活性成分的效力平均值（IC50 ± 标准差）的概述。所有表格中的数据均以平均抑制率或平均微摩尔效力表示，样本数量N≥3。阳性对照值处于可接受效力范围内（0.2 - 0.8 µM）。补充数据5展示了欧芹内酯的串联质谱数据。欧芹内酯的核磁共振光谱数据展示于补充数据（6-11）。化合物欧芹脑苷元的核磁光谱数据位于补充数据（12-15）。补充数据16展示了元胡碱A的串联质谱数据。核磁共振光谱数据展示于补充数据（17-23）。元胡碱的质谱数据位于补充数据24。元胡碱的核磁共振光谱数据展示于补充数据（25-30）。顺式2′′/3′′异构体gnididin的质谱数据位于补充数据（31）。gnididin顺式2′′/3′′异构体的补充数据位于补充数据（32-37）。化合物元花碱的质谱数据展示于补充数据38。gniditrin化合物的质谱数据及其质子核磁共振光谱数据分别位于补充数据43和44。