Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin-dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the cytosolic compartmen

NIAID Data Ecosystem40

L-methionine counteracts cocaine-conditioned place preference in mice through Glutamatergic plasticity pathways. L-methionine counteracts cocaine-conditioned place preference in mice through Glutamatergic plasticity pathways

药物成瘾分子机制

谷氨酸能突触可塑性

Drug-induced alterations in gene expression play an important role in the development of addictive behavior. Methionine has been proven to inhibit addictive behaviors of cocaine dependence. However, t

NIAID Data Ecosystem10

The dynamic translatome of retinal ganglion cell axons during assembly and maintenance of the mouse visual system. Mus musculus

轴突翻译调控

视觉系统发育

Local mRNA translation mediates the adaptive responses of axons to extrinsic signals but direct evidence that it occurs in mammalian CNS axons in vivo is scant. We developed an axon-TRAP-RiboTag appro

NIAID Data Ecosystem60

Sleep need driven oscillation of glutamatergic synaptic phenotype. Sleep need driven oscillation of glutamatergic synaptic phenotype

睡眠剥夺神经机制

谷氨酸能突触可塑性

The response to sleep loss, induced by experimental sleep deprivation (SD), provides insight into the function of sleep. Earlier observations have shown an overall increase in synaptic strength and nu

NIAID Data Ecosystem20

Additional file 3 of CPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity

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