Data set for Site Specific Lewy Pathology Circuits

NIAID Data Ecosystem2026-05-02 收录

神经退行性机制

神经细胞形态学

数据链接：

https://zenodo.org/record/14029418 数据链接链接失效反馈

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资源简介：

Processed dataset and example code related to manuscript titled: Site-Specific Seeding of Lewy Pathology Induces Distinct Pre-Motor Cellular and Dendritic Vulnerabilities in the Cortex

创建时间：

2024-11-09

Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-

神经退行性机制

细胞应激通路

Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw

NIAID Data Ecosystem100

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons

神经退行性机制

功能障碍研究

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Synaptic vesicle proteomics with age and in synucleinopathies

突触小泡蛋白质组学

神经退行性机制

Neurotransmitter release occurs through exocytosis of synaptic vesicles. α-Synuclein’s function and dysfunction in Parkinson’s disease and other synucleinopathies is tightly linked to synaptic vesicle

NIAID Data Ecosystem20

Imaging resident and recruited macrophage contributions to Wallerian degeneration. Imaging resident and recruited macrophage contributions to Wallerian degeneration

神经退行性机制

巨噬细胞功能组学

Abstract: Wallerian degeneration (WD) is a process of autonomous distal degeneration of axons upon injury. Macrophages (MP) of the peripheral nervous system (PNS) are main cellular agent controlling t

NIAID Data Ecosystem100

Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]

神经退行性机制

胶质细胞功能研究

GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp

NIAID Data Ecosystem30

Data set for Site Specific Lewy Pathology Circuits

资源简介：

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