NOVEL CAS13B ORTHOLOGUES CRISPR ENZYMES AND SYSTEMS

The present invention provides systems， methods and compositions for targeting nucleic acids. In particular， the present invention provides a novel RNA-targeting Cas13b effector protein and a non-naturally occurring or engineered RNA-targeting system comprising at least one targeting nucleic acid component such as a guide RNA or crRNA. The invention provides for systems， methods， and compositions for targeting nucleic acids. In particular， the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting Casl3b effector protein and at least one targeting nucleic acid component like a guide RNA or crRNA. The invention provides for systems， methods， and compositions for targeting nucleic acids. In particular， the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting Casl3b effector protein and at least one targeting nucleic acid component like a guide RNA or crRNA.