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SAR development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B polymerase

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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SAR development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B polymerase Descriptor: N-(cyclopropylsulfonyl)-1-(2,5-difluorobenzyl)-6-fluoro-5-methyl-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase Authors: Lesburg, C.A, Chen, K.X. Deposit date: 2011-09-26 Release date: 2012-02-01 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure-Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase. J.Med.Chem., 55, 2012
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2011-09-26
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