5Z-7-Oxozeanol inhibits the effect of TGFB1 on human gingival fibroblasts

ChEBI2015-02-26 更新2026-07-21 收录

口腔细胞生物学

TGF-β信号通路调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-65069 数据链接链接失效反馈

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5Z-7-Oxozeanol inhibits the effect of TGFB1 on human gingival fibroblasts

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2015-02-26

Wip1 regulates Smad4 phosphorylation and inhibits TGF-? signaling

TGF-β信号通路调控

磷酸酶与肿瘤抑制

The tumor suppressor Smad4, a key mediator of the TGF-?/BMP pathways, is essential for development and tissue homeostasis. Phosphorylation of Smad4 in its linker region catalyzed by the mitogen-activa

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Galunisertib (LY2157299), a transforming growth factor-β receptor I kinase inhibitor, attenuates acute pancreatitis in rats

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Galunisertib (LY2157299), a selective ATP-mimetic inhibitor of TGF-β receptor I (TGF-βRI), is the only known TGF-β pathway inhibitor. In the present study, we investigated the effect of galunisertib o

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A High-dose of genistein down-regulates TGF-beta pathway genes in human uterine leiomyoma cells

子宫肌瘤分子机制

TGF-β信号通路调控

High doses of genistein show an inhibitory effect on uterine leiomyoma (UtLM) cell proliferation. Using microarray analysis and Ingenuity Pathways AnalysisTM, we identified genes (up- or down-regulate

NIAID Data Ecosystem50

RNA-seq in Hs578T cells stimulated with TGF-Ã

乳腺癌转录组学

TGF-β信号通路调控

Transforming growth factor-Ã (TGF-Ã) comprises a key component in the tumor microenvironment. It is reported that TGF-Ã can be pro-tumorigenic or anti-tumorigenic depending on various contexts. Som

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Study of three-dimensional structure of chromatin through a 4C-seq experiment in mouse NSC shControl and shJMJD3 upon TGFβ treatment [Chst8]

染色质三维构象分析

TGF-β信号通路调控

In this study we analyzed how multiple enhancers arrange in the 3D-space to control the activation of a specific promoter. Specifically, we did a 4C-seq experiment on a ~374 Kb locus where enhancers a

NIAID Data Ecosystem70

5Z-7-Oxozeanol inhibits the effect of TGFB1 on human gingival fibroblasts

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