UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma [RNA-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP363353
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资源简介:
RNA sequening was performed to understand the role of UHRF1 in regulation of gene expression in KRAS mutant lung cancer cell lines. Knock-down of both UHRF1 and KRAS leads to significant and overlapping changes in gene expression in both cell lines. Overall design: Two KRAS mutant lung cancer cell lines were used (A549, H358). Each cell line was treated with control siRNA (siNeg), anti-KRAS siRNA (siKRAS) or anti-UHRF1 siRNA (siUHRF1) in 3 biological replicates.
创建时间:
2023-07-15



