Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). Reported haplotype lengths range from 67 to 269 kb and contain 4 to 18 genes. The region has certain p
Major Histocompatibility Complex (MHC) genes encode proteins involved in the recognition of parasite-derived antigens. Their extreme polymorphism is presumed to be driven by coevolution with parasites
This resource describes fundamental features of the immune system (frequency of leukocyte subpopulations, cell surface protein expression) in a large cohort of twins. An accompanying manuscript uses a