Bromodomain Containing Protein 4 (BRD4) Regulates Inducible Expression Of Its Interactome In The Innate Response To Respiratory Syncytial Virus

We examine the effect of a selective BRD4 inhibitor n the epithelial response to RSV infection. Wild type human small airway epithelial cells were infected in the absence or prescend of ZL0454. 24 h later, RNA was extracted and subjected to short read illumina RNA Seq. wild type small airway epithelial cells were mock or RSV infected for 24 h prior to RNA seq. Cells were treated in the absence or presence of the BRD4 inhibitor, ZL0454