Antidepressants fluoxetine mediates endoplasmic reticulum stress and autophagy of Non-small cell lung cancer cells through ATF4-AKT-mTOR signaling pathway

In order to investigate the specific mechanism of fluoxetine, we chose H460 cells that were more sensitive to the drug RNA sequencing (RNA-seq) was used to study the transcriptome of cells treated with fluoxetine and analyze the difference with control treatment