Human PARP-1 bound to NAD+ analog benzamide adenine dinucleotide (BAD)
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Human PARP-1 bound to NAD+ analog benzamide adenine dinucleotide (BAD) Descriptor: Poly [ADP-ribose] polymerase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4R,5S)-5-(3-carbamoylphenyl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name) Authors: Pascal, J.M, Langelier, M.F. Deposit date: 2017-10-31 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: NAD+analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains. Nat Commun, 9, 2018
创建时间：
2017-10-31
