Evidences of a MYC-driven precursor-B cell acute lymphoblastic leukemia (ALL) arising in the zebrafish rag2:hMYC T-cell ALL model. Evidences of a MYC-driven precursor-B cell acute lymphoblastic leukemia (ALL) arising in the zebrafish rag2:hMYC T-cell ALL model

GFP+ leukemia arising in young adult zebrafish (6 month) were FACS-purified for RNA extraction and hybridization on Affymetrix microarrays. Two zebrafish ALL models included in this study, hMYC;GFP and hlk line, to investigate differences and similarities of leukemia arising in animals with different genetic background. Overall design: Gene expression profiling of GFP+ Acute Lymphoblastic Leukemia (ALL) FACS-purified from 10 hMYC;GFP and 3 hlk individual fish.