Selection of an evolutionary model for the EV-A71 VP1 sequence dataset, through comparison of marginal likelihood.

The analyses were done with the SRD06 substitution model and a relaxed molecular clock model implementing either an uncorrelated exponential (UCED) or an uncorrelated lognormal (UCLN) distribution of clock rates among the lineages. The molecular clock and demographic models were determined by calculating the marginal likelihoods of the data conditional on all the evolutionary and demographic model parameters. The highest log marginal likelihood values indicate the best fit model.