Glycine promotes the synthesis of inosine monophosphate in hybrid bream by activating the glycyl-tRNA synthetase and synergistically enhancing the pentose phosphate pathway.

Studies have shown that the supplementation of glycine significantly promotes the synthesis and accumulation of IMP in the myoblast cells of hybrid carp. Through transcriptome analysis, it was found that the mechanism of action involves two mechanisms: by activating the purine biosynthesis pathway and by amplifying the flux of the pentose phosphate pathway through glutathione synthesis, thereby ensuring the adequate supply of metabolic precursors required for IMP production.