Integrating circulating microRNAs with epidemiological factors enhances breast cancer detection across subtypes: screening phase [miRNA-Seq]

Exploratory small RNA sequencing analysis of circulating miRNAs in serum samples from 40 women (30 breast cancer cases and 10 controls) recruited within the MCC-Spain study. Overall design: Serum samples were collected prior to treatment. Total RNA was extracted and small RNA libraries were prepared using QIAseq miRNA Library Kit and sequenced on an Illumina NextSeq 500 platform. Processed miRNA-level count data are provided. This screening phase was used for candidate biomarker selection and excluded from validation analyses. Groups: A (Controls), B (screening), C (free-disease survivorship) and D (without free-disease survivorship).