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Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1335

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6gxq
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Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1335 Descriptor: 3-[5-[(4aR,8aS)-4-OXIDANYLIDENE-3-PROPAN-2-YL-4a,5,8,8a-TETRAHYDROPHTHALAZIN-1-YL]-2-METHOXY-PHENYL]-N-(PHENYLMETHYL)PROP-2-YNAMIDE, GLYCEROL, GUANIDINE, ... Authors: Singh, A.K, Brown, D.G. Deposit date: 2018-06-27 Release date: 2019-07-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorg.Med.Chem., 27, 2019
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2018-06-27
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