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Complex between MTH1 and compound 1 (a 7-azaindole-4-ester derivative)

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6f20
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Complex between MTH1 and compound 1 (a 7-azaindole-4-ester derivative) Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, Ethyl 1H-pyrrolo[2,3-b]pyridine-4-carboxylate, ... Authors: Viklund, J, Talagas, A, Tresaugues, L, Andersson, M, Ericsson, U, Forsblom, R, Ginman, T, Hallberg, K, Lindstrom, J, Persson, L, Silvander, C, Rahm, F. Deposit date: 2017-11-23 Release date: 2018-03-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design. J. Med. Chem., 61, 2018
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2017-11-23
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