Distinguishing Features of Type 1 and Type 2 Leprosy Reactions.

aBT = borderline tuberculoid; BB = borderline borderline; BL = borderline lepromatous; LL = lepromatous.bSometimes silent neuritis may be present, manifested by nerve function impairment (loss of sensations and/or muscle weakness) without skin inflammation.cSkin biopsy may present some key features such as dermal edema, granuloma edema, and presence of giant cells and plasma cells.dSkin biopsy may present a mixed dermal infiltrate of neutrophils and lymphocytes and fragmented bacilli in macrophages.eFor mild reactions, non-steroidal anti-inflammatory drugs may be sufficient. Prednisone or prednisolone are used for severe signs and symptoms; for alternative treatment options, see Table 2.