Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells
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https://www.ncbi.nlm.nih.gov/sra/SRP306756
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资源简介：
Loss of Pten and inhibition of PI3K induced apoptosis of hematopoietic stem/progenitor cells upon endothelial to hematopoietic transition and surviving hematopoietic stem/progenitor cells committed to all blood lineages but displayed reduced stemness Overall design: AGMs (36hpf) or CHTs (5dpf) were dissected and dissociated, using FACS sorting HSPCs were isolated and single cell RNA seq was performed.
创建时间：
2021-05-07
