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Approach to the Synthesis of Cladiell-11-ene-3,6,7-triol

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https://figshare.com/articles/dataset/Approach_to_the_Synthesis_of_Cladiell_11_ene_3_6_7_triol/3064621
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The synthesis of an advanced intermediate in the synthesis of the title compound has been achieved. Key steps include an Ireland−Claisen rearrangement to install the C7 tertiary alcohol stereocenter, an SN2‘ reaction of an alkoxymethyl Cu reagent, and a diastereoselective Re-catalyzed allylic alcohol transposition.
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2016-02-29
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