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HIV Protease, pseudo-symmetric inhibitors

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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HIV Protease, pseudo-symmetric inhibitors Descriptor: V-1 protease, methyl [(1S)-1-{[(1R,3S,4S)-4-{[(2S)-3,3-dimethyl-2-{3-[(6-methylpyridin-2-yl)methyl]-2-oxo-2,3-dihydro-1H-imidazol-1-yl}butanoyl]amino}-3-hydroxy-5-phenyl-1-(4-pyridin-2-ylbenzyl)pentyl]carbamoyl}-2,2-dimethylpropyl]carbamate Authors: Stoll, V.S. Deposit date: 2009-03-02 Release date: 2009-05-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.7 Å) Cite: 2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects. J.Med.Chem., 52, 2009

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2009-03-02
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