Investigating effect of TMEM184B mutation on hippocampal gene expression in 5 month and 15 month old mice

The objective of this study was to determine whether TMEM184B influenced the expression of genes important for neuronal function or memory. Overall design: We isolated hippocampus tissue from 3-4 mice of wild type or TMEM184B gene trap mutant mice at 5 months and 15 months of age. We then isolated total RNA and performed paired-end bulk RNA sequencing