Geographic, clinical and biological characteristics of L. donovani strains.

a = in vitro antimonial susceptibility as described in Rijal et al.[8], A.I. or activity index is defined as the ratio of the EC50 of a particular isolate or clone versus the EC50 of reference isolate sensitive to SSG. The activity index is used to express the in vitro susceptibility of that tested isolate or clone, isolates or clones with an activity index between 1 and 2 are considered as sensitive to antimonials (white background), while those showing an activity index between 3 and 6 are considered to be in vitro resistant (grey background), b = experiment done with clinical isolates, c = experiment done with clones derived from clinical isolates.