This project reveals the role of Gcn4 in methionine dependent regulation of anabolic response. Using ChIP seq and RNA seq approaches, we identify the direct and indirect targets of Gcn4 under methioni
Cold and nutrient activated brown adipose tissue (BAT) is capable of increasing systemic energy expenditure via uncoupled respiration and secretion of endocrine factors thereby protecting mice against
KRAP (Ki-ras-induced actin-interacting protein) is a cytoskeleton-associated protein and a ubiquitous protein among tissues, originally identified as a cancer-related molecule. KRAP-deficient (KRAP-/-
We purified mouse duodenal cells from organoids derived from two different transgenic mouse lines (GIP-Cre tdRFP, SST-Cre tdRFP), and identified transcripts enriched in metformin-treated cells. Overal
