Enantioselective Total Synthesis of (+)-Nocardioazine B
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https://figshare.com/articles/dataset/Enantioselective_Total_Synthesis_of_-Nocardioazine_B/7321208
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资源简介：
In
this paper, we report an enantioselective total synthesis of (+)-nocardioazine
B, a prenylated hexahydropyrrolo[2,3-b]indole (HPI)
alkaloid with a central 2,5-diketopiperazine (DKP) ring. The key step
in our synthetic route is a copper-catalyzed sequential arylation–alkylation
of o-haloanilide derivatives. Based on this transformation,
the construction of C3 all-carbon quaternary stereocenters presented
in the HPI systems was achieved with high yields and excellent diastereoselectivity.
创建时间：
2018-11-09
