Transcriptional alterations in Type II Rothmund-Thompson Syndrome
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https://www.ncbi.nlm.nih.gov/sra/SRP320554
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资源简介:
We generated induced pluripotent stem cell lines (iPSCs) from paired RTS patient/ parental control fibroblasts. These iPSCs were differentiated to mesenchymal stem cells (MSCs), and then to osteoblasts. We next compared the transcriptional profiles of MSCs, pre-osteoblasts, and osteoblasts. Overall design: Comparison of Type II RTS (RECQL4 mut/mut) iPCS derived mesenchymal stem celks, early osteoblasts, and late osteoblasts to Family controls (RECQL4wt/mut).
创建时间:
2023-01-18



