Sox17 and Ã-catenin co-occupy Wnt-responsive enhancers to govern the endodermal gene regulatory network
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https://www.ncbi.nlm.nih.gov/sra/SRP256469
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资源简介:
We report the ChIP-seq analysis of Sox17 genome-wide binding and its loss-of-function transcriptomic analysis of both Sox17 and Ctnnb1 (beta-catenin) by RNA-seq. Overall design: ChIP-seq was performed to detect endogenous Sox17 binding (N&F stage 10.5) and RNA-seq was used to assess gene expression changes in Sox17 (N&F stages 9, 9.5, 10, 10.5, 11, 12) or Ctnnb1 (N&F stages 7, 8, 9, 9.5, 10, 10.5, 11, 12) in morpholino antisense oligo injected versus uninjected control embryos
创建时间:
2020-09-17



