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Effect of Ythdf2 in haematopoiesis [RNA-seq]

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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The mRNA m6A reader YTHDF2 is overexpressed in human acute myeloid leukaemias. To understand the role of YTHDF2 in normal haematopoiesis and ageing, we performed SMART-seq on haematopoietic stem cells (HSCs) derived from young and aged (1 year old) mice. In parallel, to identify transcripts likely methylated in HSCs we performed meRIP-seq analysis of c-Kit+ cells.

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2022-02-20
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