Global consensus map and dynamics of human transcription factor footprints

Data associated with publication "Global reference mapping and dynamics of human transcription factor footprints". https://doi.org/10.1101/2020.01.31.927798 These data describe digital genomic footprints derived from 243 human biosamples. Metadata with biosample annotation and ENCODE project accessions in Excel format (Extended Data Table 1): Consensus_footprints_metadata.xlsx Raw footprint call within individual datasets at a FDR cutoff of 0.01 (additional levels of FDR thresholding can be made available by request). The following tarball contains 243 BED-formatted files, each corresponding to an individual dataset. (Extended Data File 1). Footprints_per_sample.0q01.tar.gz Tab-delimited files with consensus footprint coordinates and overlaps with TF recognition sequence matches in human genome build GRCh38/hg38. The legend file contains column definitions in detail (Extended Data File 2). Consensus_footprints_and_motifs_hg38.bed.gz Consensus_footprints_and_motifs_legend.txt Footprint occupancy matrix of index footprints (rows) vs. biosamples (columns). Rows are same order as the consensus footprint file and columns are same order as in the metadata files (Extended Data Files 3 and 4). Consensus_footprints_and_motifs_matrix_full_hg38.txt.gz (Values are -log(1-posterior)) Consensus_footprints_and_motifs_matrix_binary_hg38.txt.gz (binary occupancy matrix, where footprints with posterior footprint probability >0.99 are considered occupied) Motif clustering metdata in Excel format (Extended Data Table 2): Motif_clustering_metadata.xlsx Contact: Jeff Vierstra ([e-mail])