Aflatoxin B1 attenuates endocrine function, protein synthesis and energy production of human primary trophoblast. Aflatoxin B1 attenuates endocrine function, protein synthesis and energy production of human primary trophoblast

Aflatoxin B1 (AFB1) is a mycotoxin produced by Aspergillus flavus and A. parasiticus. AFB1 targeted gene expression profiles were determined in human primary trophoblast cells, isolated from full term placentae after delivery, and exposed to 1 µM AFB1 for 72 hours. Gene expression profiling conducted with human HT-12 expression beadchips Overall design: Total RNA obtained from trophoblast cultures 72 hours after AFB1 treatment compared to untreated controls, analyzed with Illumina HT-12 microarray. Complete raw data were not available.