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CDK2 and small molecular inhibitor L14

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Protein Data Bank Japan2025-11-26 更新2026-06-30 收录
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https://pdbj.org/mine/summary/8ypw
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CDK2 and small molecular inhibitor L14 Descriptor: Cyclin-dependent kinase 2, methyl 3-[4-[3-[[3-[(1-ethylsulfonylpiperidin-4-yl)carbamoyl]-1~{H}-pyrazol-4-yl]carbamoyl]-2,4-bis(fluoranyl)phenyl]piperidin-1-yl]-3-oxidanylidene-propanoate Authors: Ge, S. Deposit date: 2024-03-18 Release date: 2025-09-24 Last modified: 2025-11-26 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Fulcrum Occupancy-Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2-Cyclin A2 Interaction Inhibitors. Angew.Chem.Int.Ed.Engl., 64, 2025
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2024-03-18
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